Performance Evaluation of Montelukast Pediatric Formulations: Part II — a PBPK Modelling Approach

This study aimed to build a physiologically based pharmacokinetic (PBPK) model coupled with age-appropriate in vitro dissolution data to describe drug performance in adults and pediatric patients. Montelukast sodium was chosen as a model drug. Two case studies were investigated: case study 1 focused...

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Detalles Bibliográficos
Autores principales: Guimarães, Mariana, Vertzoni, Maria, Fotaki, Nikoletta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816611/
https://www.ncbi.nlm.nih.gov/pubmed/35013803
http://dx.doi.org/10.1208/s12248-021-00662-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816611/
https://www.ncbi.nlm.nih.gov/pubmed/35013803
http://dx.doi.org/10.1208/s12248-021-00662-1

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