Assessment of Abrasion-Induced Visual Defects in Twin Screw Wet Granulation Using Wall Friction Measurements

Starting point of the presented study were abrasion effects occurring during a twin screw wet granulation (TSG) process of a new chemical entity (NCE) formulation, resulting in gray spots on the final tablets. Several actions and systematic changes of equipment and process parameter settings of TSG...

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Detalles Bibliográficos
Autores principales: Menth, Judith, Maus, Martin, Wagner, Karl G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816612/
https://www.ncbi.nlm.nih.gov/pubmed/34984575
http://dx.doi.org/10.1208/s12249-021-02140-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816612/
https://www.ncbi.nlm.nih.gov/pubmed/34984575
http://dx.doi.org/10.1208/s12249-021-02140-5

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