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Cannabidiol activates PINK1-Parkin-dependent mitophagy and mitochondrial-derived vesicles

The PINK1/Parkin pathway plays an important role in maintaining a healthy pool of mitochondria. Activation of this pathway can lead to apoptosis, mitophagy, or mitochondrial-derived vesicle formation, depending on the nature of mitochondrial damage. The signaling by which PINK/Parkin activation lead...

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Detalles Bibliográficos
Autores principales: Ramirez, Adrian, Old, William, Selwood, David L., Liu, Xuedong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816654/
https://www.ncbi.nlm.nih.gov/pubmed/34915361
http://dx.doi.org/10.1016/j.ejcb.2021.151185