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Multidimensional Dynamics of the Proteome in the Neurodegenerative and Aging Mammalian Brain
The amount of any given protein in the brain is determined by the rates of its synthesis and destruction, which are regulated by different cellular mechanisms. Here, we combine metabolic labeling in live mice with global proteomic profiling to simultaneously quantify both the flux and amount of prot...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
American Society for Biochemistry and Molecular Biology
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816717/ https://www.ncbi.nlm.nih.gov/pubmed/34979241 http://dx.doi.org/10.1016/j.mcpro.2021.100192 |