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Characterization of the AGR2 Interactome Uncovers New Players of Protein Disulfide Isomerase Network in Cancer Cells

Anterior gradient 2 (AGR2) is an endoplasmic reticulum (ER)-resident protein disulfide isomerase (PDI) known to be overexpressed in many human epithelial cancers and is involved in cell migration, cellular transformation, angiogenesis, and metastasis. This protein inhibits the activity of the tumor...

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Detalles Bibliográficos
Autores principales: Bouchalova, Pavla, Sommerova, Lucia, Potesil, David, Martisova, Andrea, Lapcik, Petr, Koci, Veronika, Scherl, Alex, Vonka, Petr, Planas-Iglesias, Joan, Chevet, Eric, Bouchal, Pavel, Hrstka, Roman
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816719/
https://www.ncbi.nlm.nih.gov/pubmed/34929376
http://dx.doi.org/10.1016/j.mcpro.2021.100188