Cargando…

βig-h3-structured collagen alters macrophage phenotype and function in pancreatic cancer

Macrophages play an important role in immune and matrix regulation during pancreatic adenocarcinoma (PDAC). Collagen deposition massively contributes to the physical and functional changes of the tissue during pathogenesis. We investigated the impact of thick collagen fibers on the phenotype and fun...

Descripción completa

Detalles Bibliográficos
Autores principales: Bachy, Sophie, Wu, Zhichong, Gamradt, Pia, Thierry, Kevin, Milani, Pascale, Chlasta, Julien, Hennino, Ana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816720/
https://www.ncbi.nlm.nih.gov/pubmed/35146384
http://dx.doi.org/10.1016/j.isci.2022.103758