SMAD4 mutations do not preclude epithelial–mesenchymal transition in colorectal cancer

Transforming growth factor beta (TGFβ) superfamily signaling is a prime inducer of epithelial-mesenchymal transitions (EMT) that foster cancer cell invasion and metastasis, a major cause of cancer-related deaths. Yet, TGFβ signaling is frequently inactivated in human tumor entities including colorec...

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Detalles Bibliográficos
Autores principales: Frey, Patrick, Devisme, Antoine, Rose, Katja, Schrempp, Monika, Freihen, Vivien, Andrieux, Geoffroy, Boerries, Melanie, Hecht, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816731/
https://www.ncbi.nlm.nih.gov/pubmed/34857888
http://dx.doi.org/10.1038/s41388-021-02128-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816731/
https://www.ncbi.nlm.nih.gov/pubmed/34857888
http://dx.doi.org/10.1038/s41388-021-02128-2

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