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Involvement of neuronal and muscular Trk-fused gene (TFG) defects in the development of neurodegenerative diseases

Trk-fused gene (TFG) mutations have been identified in patients with several neurodegenerative diseases. In this study, we attempted to clarify the effects of TFG deletions in motor neurons and in muscle fibers, using tissue-specific TFG knockout (vMNTFG KO and MUSTFG KO) mice. vMNTFG KO, generated...

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Detalles Bibliográficos
Autores principales: Yamamotoya, Takeshi, Hasei, Shun, Akasaka, Yasuyuki, Ohata, Yukino, Nakatsu, Yusuke, Kanna, Machi, Fujishiro, Midori, Sakoda, Hideyuki, Ono, Hiraku, Kushiyama, Akifumi, Misawa, Hidemi, Asano, Tomoichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816932/
https://www.ncbi.nlm.nih.gov/pubmed/35121777
http://dx.doi.org/10.1038/s41598-022-05884-7