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Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment

Sporadic apoptosis of tumour cells is a commonly observed feature of colorectal cancer (CRC) and strongly correlates with adverse patient prognosis. The uptake of apoptotic cell debris by neutrophils induces a non-inflammatory, pro-regenerative, and hence potentially pro-tumorigenic phenotype. In th...

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Detalles Bibliográficos
Autores principales: Schimek, Vanessa, Strasser, Katharina, Beer, Andrea, Göber, Samantha, Walterskirchen, Natalie, Brostjan, Christine, Müller, Catharina, Bachleitner-Hofmann, Thomas, Bergmann, Michael, Dolznig, Helmut, Oehler, Rudolf
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816934/
https://www.ncbi.nlm.nih.gov/pubmed/35121727
http://dx.doi.org/10.1038/s41419-022-04585-3