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Tumour cell apoptosis modulates the colorectal cancer immune microenvironment via interleukin-8-dependent neutrophil recruitment
Sporadic apoptosis of tumour cells is a commonly observed feature of colorectal cancer (CRC) and strongly correlates with adverse patient prognosis. The uptake of apoptotic cell debris by neutrophils induces a non-inflammatory, pro-regenerative, and hence potentially pro-tumorigenic phenotype. In th...
Autores principales: | Schimek, Vanessa, Strasser, Katharina, Beer, Andrea, Göber, Samantha, Walterskirchen, Natalie, Brostjan, Christine, Müller, Catharina, Bachleitner-Hofmann, Thomas, Bergmann, Michael, Dolznig, Helmut, Oehler, Rudolf |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816934/ https://www.ncbi.nlm.nih.gov/pubmed/35121727 http://dx.doi.org/10.1038/s41419-022-04585-3 |
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