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Refined characterization of circulating tumor DNA through biological feature integration

Circulating tumor DNA (ctDNA) in blood plasma is present at very low concentrations compared to cell-free DNA (cfDNA) of non-tumor origin. To enhance ctDNA detection, recent studies have been focused on understanding the non-random fragmentation pattern of cfDNA. These studies have investigated frag...

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Detalles Bibliográficos
Autores principales: Markus, Havell, Chandrananda, Dineika, Moore, Elizabeth, Mouliere, Florent, Morris, James, Brenton, James D., Smith, Christopher G., Rosenfeld, Nitzan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816939/
https://www.ncbi.nlm.nih.gov/pubmed/35121756
http://dx.doi.org/10.1038/s41598-022-05606-z