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Somatic PMK-1/p38 signaling links environmental stress to germ cell apoptosis and heritable euploidy

Inheritance of stable and euploid genomes is a prerequisite for species maintenance. The DNA damage response in germ cells controls the integrity of heritable genomes. Whether and how somatic stress responses impact the quality control of germline genomes has remained unclear. Here, we show that PMK...

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Detalles Bibliográficos
Autores principales: Soltanmohammadi, Najmeh, Wang, Siyao, Schumacher, Björn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8816960/
https://www.ncbi.nlm.nih.gov/pubmed/35121747
http://dx.doi.org/10.1038/s41467-022-28225-8