Synthetic adiponectin-receptor agonist, AdipoRon, induces glycolytic dependence in pancreatic cancer cells

Obesity creates a localized inflammatory reaction in the adipose, altering secretion of adipocyte-derived factors that contribute to pathologies including cancer. We have previously shown that adiponectin inhibits pancreatic cancer by antagonizing leptin-induced STAT3 activation. Yet, the effects of...

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Detalles Bibliográficos
Autores principales: Manley, Sharon J., Olou, Appolinaire A., Jack, Jarrid L., Ruckert, Mariana T., Walsh, R. McKinnon, Eades, Austin E., Bye, Bailey A., Ambrose, Joe, Messaggio, Fanuel, Anant, Shrikant, VanSaun, Michael N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817044/
https://www.ncbi.nlm.nih.gov/pubmed/35121743
http://dx.doi.org/10.1038/s41419-022-04572-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817044/
https://www.ncbi.nlm.nih.gov/pubmed/35121743
http://dx.doi.org/10.1038/s41419-022-04572-8

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