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Placental genomics mediates genetic associations with complex health traits and disease

As the master regulator in utero, the placenta is core to the Developmental Origins of Health and Disease (DOHaD) hypothesis but is historically understudied. To identify placental gene-trait associations (GTAs) across the life course, we perform distal mediator-enriched transcriptome-wide associati...

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Detalles Bibliográficos
Autores principales: Bhattacharya, Arjun, Freedman, Anastasia N., Avula, Vennela, Harris, Rebeca, Liu, Weifang, Pan, Calvin, Lusis, Aldons J., Joseph, Robert M., Smeester, Lisa, Hartwell, Hadley J., Kuban, Karl C. K., Marsit, Carmen J., Li, Yun, O’Shea, T. Michael, Fry, Rebecca C., Santos, Hudson P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817049/
https://www.ncbi.nlm.nih.gov/pubmed/35121757
http://dx.doi.org/10.1038/s41467-022-28365-x