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Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States

BACKGROUND: Hepatocellular carcinoma (HCC) patient‐derived xenograft (PDX) models hold potential to advance knowledge in HCC biology to help improve systemic therapies. Beside hepatitis B virus‐associated tumors, HCC is poorly established in PDX. METHODS: PDX formation from fresh HCC biopsies were o...

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Detalles Bibliográficos
Autores principales: Zou, Chenhui, El Dika, Imane, Vercauteren, Koen O. A., Capanu, Marinela, Chou, Joanne, Shia, Jinru, Pilet, Jill, Quirk, Corrine, Lalazar, Gadi, Andrus, Linda, Kabbani, Mohammad, Yaqubie, Amin, Khalil, Danny, Mergoub, Taha, Chiriboga, Luis, Rice, Charles M., Abou‐Alfa, Ghassan K., de Jong, Ype P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817074/
https://www.ncbi.nlm.nih.gov/pubmed/34951132
http://dx.doi.org/10.1002/cam4.4375