Cargando…

Mouse characteristics that affect establishing xenografts from hepatocellular carcinoma patient biopsies in the United States

BACKGROUND: Hepatocellular carcinoma (HCC) patient‐derived xenograft (PDX) models hold potential to advance knowledge in HCC biology to help improve systemic therapies. Beside hepatitis B virus‐associated tumors, HCC is poorly established in PDX. METHODS: PDX formation from fresh HCC biopsies were o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zou, Chenhui, El Dika, Imane, Vercauteren, Koen O. A., Capanu, Marinela, Chou, Joanne, Shia, Jinru, Pilet, Jill, Quirk, Corrine, Lalazar, Gadi, Andrus, Linda, Kabbani, Mohammad, Yaqubie, Amin, Khalil, Danny, Mergoub, Taha, Chiriboga, Luis, Rice, Charles M., Abou‐Alfa, Ghassan K., de Jong, Ype P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Clinical Cancer Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817074/ https://www.ncbi.nlm.nih.gov/pubmed/34951132 http://dx.doi.org/10.1002/cam4.4375

Ejemplares similares

Phase II trial of sorafenib and doxorubicin in patients with advanced hepatocellular carcinoma after disease progression on sorafenib
por: El Dika, Imane, et al.
Publicado: (2020)

Experimental Variables that Affect Human Hepatocyte AAV Transduction in Liver Chimeric Mice
por: Zou, Chenhui, et al.
Publicado: (2020)

Treatment options after sorafenib failure in patients with hepatocellular carcinoma
por: Dika, Imane El, et al.
Publicado: (2017)

Expansion, in vivo–ex vivo cycling, and genetic manipulation of primary human hepatocytes
por: Michailidis, Eleftherios, et al.
Publicado: (2020)

Hepatocellular carcinoma, novel therapies on the horizon
por: El Dika, Imane, et al.
Publicado: (2020)

Analysis of Hepatitis C Virus Particle Heterogeneity in Immunodeficient Human Liver Chimeric fah-/- Mice
por: Andreo, Ursula, et al.
Publicado: (2017)

Congenital cardiac liver cirrhosis with combined hepatocellular-cholangiocarcinoma—a case report
por: El Dika, Imane, et al.
Publicado: (2022)

Effect of FGFR2 Alterations on Overall and Progression-Free Survival in Patients Receiving Systemic Therapy for Intrahepatic Cholangiocarcinoma
por: Abou-Alfa, Ghassan K., et al.
Publicado: (2022)

Viral Diseases of the Liver
por: Lalazar, Gadi, et al.
Publicado: (2013)

Integrative analysis of functional genomic annotations and sequencing data to identify rare causal variants via hierarchical modeling
por: Capanu, Marinela, et al.
Publicado: (2015)

Phase 1b study of galunisertib and ramucirumab in patients with advanced hepatocellular carcinoma
por: Harding, James J., et al.
Publicado: (2021)

A Phase Ib, Open‐Label Study of Dalantercept, an Activin Receptor‐Like Kinase 1 Ligand Trap, plus Sorafenib in Advanced Hepatocellular Carcinoma
por: Abou‐Alfa, Ghassan K., et al.
Publicado: (2018)

Assessment of insulin resistance by a (13)C glucose breath test: a new tool for early diagnosis and follow-up of high-risk patients
por: Mizrahi, Meir, et al.
Publicado: (2010)

An RNA-based system to study hepatitis B virus replication and evaluate antivirals
por: Yu, Yingpu, et al.
Publicado: (2023)

Mitral Stenosis Presenting with Acute Hearing Loss
por: Gur, Chamutal, et al.
Publicado: (2006)

An Interesting Case of Isolated False-Reactive Hepatitis B Surface Antigen
por: Costa, Victoria, et al.
Publicado: (2021)

Patient advocacy and the future of systemic therapies in liver cancer: an interview with Ghassan Abou-Alfa
por: Abou-Alfa, Ghassan
Publicado: (2020)

Identification of Rare Causal Variants in Sequence-Based Studies: Methods and Applications to VPS13B, a Gene Involved in Cohen Syndrome and Autism
por: Ionita-Laza, Iuliana, et al.
Publicado: (2014)

Pancreatic adenocarcinoma: insights into patterns of recurrence and disease behavior
por: Sahin, Ibrahim H., et al.
Publicado: (2018)

Targeting BCL-XL in fibrolamellar hepatocellular carcinoma
por: Shebl, Bassem, et al.
Publicado: (2022)

ESMO presidential symposium wrap up: the ClarIDHy trial
por: Abou-Alfa, Ghassan K
Publicado: (2020)

Oncogenic Addiction of Fibrolamellar Hepatocellular Carcinoma to the Fusion Kinase DNAJB1-PRKACA
por: Neumayer, Christoph, et al.
Publicado: (2023)

Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data
por: Zack, Travis, et al.
Publicado: (2023)

CT features of HER2-mutant lung adenocarcinomas
por: Sawan, Peter, et al.
Publicado: (2018)

Global Oncology Medical Diplomacy Working Group Inaugural Meeting: Defining Worldwide Barriers to Germline Genomics in Cancer Prevention and Management
por: Abou-Alfa, Ghassan K., et al.
Publicado: (2023)

An Open‐Label, Multicenter, Phase I, Dose Escalation Study with Phase II Expansion Cohort to Determine the Safety, Pharmacokinetics, and Preliminary Antitumor Activity of Intravenous TKM‐080301 in Subjects with Advanced Hepatocellular Carcinoma
por: El Dika, Imane, et al.
Publicado: (2018)

A phase II study of gemcitabine and cisplatin plus sorafenib in patients with advanced biliary adenocarcinomas
por: Lee, J K, et al.
Publicado: (2013)

IDEAL-IQ in an oncologic population: meeting the challenge of concomitant liver fat and liver iron
por: Eskreis-Winkler, Sarah, et al.
Publicado: (2018)

Micro-computed tomography: A novel diagnostic technique for the evaluation of gastrointestinal specimens
por: Kawata, Noboru, et al.
Publicado: (2021)

Diffusion-weighted MRI and histogram analysis: assessment of response to neoadjuvant chemotherapy in nephroblastoma
por: Hötker, Andreas M., et al.
Publicado: (2021)

Evolving treatment approaches for the management of metastatic castration-resistant prostate cancer – role of radium-223
por: Mukherji, Deborah, et al.
Publicado: (2014)

Sunitinib Induced Thrombotic Thrombocytopenic Purpura in addition to Severe Hypothyroidism: A Case Report and Review of the Literature
por: El Dika, Imane, et al.
Publicado: (2014)

Alleviation of insulin resistance and liver damage by oral administration of Imm124-E is mediated by increased Tregs and associated with increased serum GLP-1 and adiponectin: results of a phase I/II clinical trial in NASH
por: Mizrahi, Meir, et al.
Publicado: (2012)

Early-Stage Loss of GALNT6 Predicts Poor Clinical Outcome in Colorectal Cancer
por: Ogawa, Makiko, et al.
Publicado: (2022)

Pancreatic cancer stem cells may define tumor stroma characteristics and recurrence patterns in pancreatic ductal adenocarcinoma
por: Askan, Gokce, et al.
Publicado: (2021)

Tumor stromal nicotinamide N-methyltransferase overexpression as a prognostic biomarker for poor clinical outcome in early-stage colorectal cancer
por: Ogawa, Makiko, et al.
Publicado: (2022)

Characterization of Live-Attenuated Powassan Virus Vaccine Candidates Identifies an Efficacious Prime-Boost Strategy for Mitigating Powassan Virus Disease in a Murine Model
por: Cheung, Andrew M., et al.
Publicado: (2023)

Non coding RNA analysis in fibrolamellar hepatocellular carcinoma
por: Farber, Benjamin A., et al.
Publicado: (2017)

STAT1 as a potential prognosis marker for poor outcomes of early stage colorectal cancer with microsatellite instability
por: Tanaka, Atsushi, et al.
Publicado: (2020)

The effect of medical students’ gender, ethnicity and attitude towards poetry-reading on the evaluation of a required, clinically-integrated poetry- based educational intervention
por: Muszkat, Mordechai, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_rdaafbv1njala0euvhle5tr20h