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Analysis of CDK12 alterations in a pan‐cancer database

BACKGROUND: CDK12 inactivation leading to increased neoantigen burden has been hypothesized to sensitize tumors to immune checkpoint inhibition. Pan‐cancer data regarding the frequency of CDK12 alterations are limited. We aimed to characterize CDK12 alterations across all cancer types through real‐w...

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Detalles Bibliográficos
Autores principales: Pan, Elizabeth, Cabal, Angelo, Javier‐DesLoges, Juan, Patel, Devin, Panian, Justine, Lee, Suzanna, Shaya, Justin, Nonato, Taylor, Xu, Xiaojun, Stewart, Tyler, Rose, Brent, Shabaik, Ahmed, Cohen, Ezra, Kurzrock, Razelle, Tamayo, Pablo, McKay, Rana R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817093/
https://www.ncbi.nlm.nih.gov/pubmed/34898046
http://dx.doi.org/10.1002/cam4.4483