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Analysis of CDK12 alterations in a pan‐cancer database
BACKGROUND: CDK12 inactivation leading to increased neoantigen burden has been hypothesized to sensitize tumors to immune checkpoint inhibition. Pan‐cancer data regarding the frequency of CDK12 alterations are limited. We aimed to characterize CDK12 alterations across all cancer types through real‐w...
Autores principales: | Pan, Elizabeth, Cabal, Angelo, Javier‐DesLoges, Juan, Patel, Devin, Panian, Justine, Lee, Suzanna, Shaya, Justin, Nonato, Taylor, Xu, Xiaojun, Stewart, Tyler, Rose, Brent, Shabaik, Ahmed, Cohen, Ezra, Kurzrock, Razelle, Tamayo, Pablo, McKay, Rana R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817093/ https://www.ncbi.nlm.nih.gov/pubmed/34898046 http://dx.doi.org/10.1002/cam4.4483 |
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