Pan‐cancer analyses reveal that increased Hedgehog activity correlates with tumor immunosuppression and resistance to immune checkpoint inhibitors

BACKGROUND: Immune checkpoint inhibitors (ICIs) have shown numerous clinical benefits in multiple cancer types, but good predictive biomarkers are severely lacking. Although increasing evidence has linked Hedgehog (Hh) signaling pathway with tumor development, a systematic investigation for its pote...

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Detalles Bibliográficos
Autores principales: Jiang, Junjie, Ding, Yongfeng, Chen, Yanyan, Lu, Jun, Chen, Yiran, Wu, Guanghao, Xu, Nong, Wang, Haiyong, Teng, Lisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Bioinformatics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817099/
https://www.ncbi.nlm.nih.gov/pubmed/34841742
http://dx.doi.org/10.1002/cam4.4456

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817099/
https://www.ncbi.nlm.nih.gov/pubmed/34841742
http://dx.doi.org/10.1002/cam4.4456

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