A SARS-CoV-2 Delta variant containing mutation in the probe binding region used for RT-qPCR test in Japan exhibited atypical PCR amplification and might induce false negative result

INTRODUCTION: A recent pandemic of SARS-CoV-2 infection has caused severe health problems and substantially restricted social and economic activities. RT-qPCR plays a vital role in the diagnosis of SARS-CoV-2 infection. The N protein-coding region is widely analyzed in RT-qPCR to diagnose SARS-CoV-2...

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Detalles Bibliográficos
Autores principales: Rajib, Samiul Alam, Ogi, Yasuhiro, Hossain, Md Belal, Ikeda, Terumasa, Tanaka, Eiichi, Kawaguchi, Tatsuya, Satou, Yorifumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817104/
https://www.ncbi.nlm.nih.gov/pubmed/35144878
http://dx.doi.org/10.1016/j.jiac.2022.01.019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817104/
https://www.ncbi.nlm.nih.gov/pubmed/35144878
http://dx.doi.org/10.1016/j.jiac.2022.01.019

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