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A SARS-CoV-2 Delta variant containing mutation in the probe binding region used for RT-qPCR test in Japan exhibited atypical PCR amplification and might induce false negative result
INTRODUCTION: A recent pandemic of SARS-CoV-2 infection has caused severe health problems and substantially restricted social and economic activities. RT-qPCR plays a vital role in the diagnosis of SARS-CoV-2 infection. The N protein-coding region is widely analyzed in RT-qPCR to diagnose SARS-CoV-2...
Autores principales: | Rajib, Samiul Alam, Ogi, Yasuhiro, Hossain, Md Belal, Ikeda, Terumasa, Tanaka, Eiichi, Kawaguchi, Tatsuya, Satou, Yorifumi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Japanese Society of Chemotherapy and The Japanese Association for Infectious Diseases. Published by Elsevier Ltd.
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817104/ https://www.ncbi.nlm.nih.gov/pubmed/35144878 http://dx.doi.org/10.1016/j.jiac.2022.01.019 |
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