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A transgene-free method for rapid and efficient generation of precisely edited pigs without monoclonal selection
Gene-edited pigs for agricultural and biomedical applications are typically generated using somatic cell nuclear transfer (SCNT). However, SCNT requires the use of monoclonal cells as donors, and the time-consuming and laborious monoclonal selection process limits the production of large populations...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Science China Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817169/ https://www.ncbi.nlm.nih.gov/pubmed/35122622 http://dx.doi.org/10.1007/s11427-021-2058-2 |