A transgene-free method for rapid and efficient generation of precisely edited pigs without monoclonal selection

Gene-edited pigs for agricultural and biomedical applications are typically generated using somatic cell nuclear transfer (SCNT). However, SCNT requires the use of monoclonal cells as donors, and the time-consuming and laborious monoclonal selection process limits the production of large populations...

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Detalles Bibliográficos
Autores principales: Xu, Kui, Zhang, Xiuling, Liu, Zhiguo, Ruan, Jinxue, Xu, Changjiang, Che, Jingjing, Fan, Ziyao, Mu, Yulian, Li, Kui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science China Press 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817169/
https://www.ncbi.nlm.nih.gov/pubmed/35122622
http://dx.doi.org/10.1007/s11427-021-2058-2

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