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Frequencies of CYP2D6 genetic polymorphisms in Arab populations

CYP2D6 is a key drug-metabolizing enzyme implicated in the biotransformation of approximately 25% of currently prescribed drugs. Interindividual and interethnic differences in CYP2D6 enzymatic activity, and hence variability in substrate drug efficacy and safety, are attributed to a highly polymorph...

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Detalles Bibliográficos
Autores principales: Alali, Mousa, Ismail Al-khalil, Wouroud, Rijjal, Sara, Al-Salhi, Lana, Saifo, Maher, Youssef, Lama A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817534/
https://www.ncbi.nlm.nih.gov/pubmed/35123571
http://dx.doi.org/10.1186/s40246-022-00378-z