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Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells

BACKGROUND: Ex vivo production of induced megakaryocytes (MKs) and platelets from stem cells is an alternative approach for supplying transfusible platelets. However, it is difficult to generate large numbers of MKs and platelets from hematopoietic stem cells and progenitor cells (HSPCs). METHODS: T...

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Detalles Bibliográficos
Autores principales: Jiang, Jianan, Qin, Jinhua, Li, Jisheng, Lin, Xiaosong, Zhang, Bowen, Fan, Zeng, He, Lijuan, Zeng, Quan, Yue, Wen, Zheng, Min, Pei, Xuetao, Li, Yanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817546/
https://www.ncbi.nlm.nih.gov/pubmed/35123563
http://dx.doi.org/10.1186/s13287-022-02722-5