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Ricolinostat promotes the generation of megakaryocyte progenitors from human hematopoietic stem and progenitor cells
BACKGROUND: Ex vivo production of induced megakaryocytes (MKs) and platelets from stem cells is an alternative approach for supplying transfusible platelets. However, it is difficult to generate large numbers of MKs and platelets from hematopoietic stem cells and progenitor cells (HSPCs). METHODS: T...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817546/ https://www.ncbi.nlm.nih.gov/pubmed/35123563 http://dx.doi.org/10.1186/s13287-022-02722-5 |