Bcl-xL DNAzymes promote radiosensitivity and chemosensitivity in colorectal cancer cells via enhancing apoptosis

BACKGROUND: RNA-cleaving deoxyribozymes (DNAzymes) are catalytic deoxyribonucleic acid molecules that have become a promising new class of gene suppressors by binding and cleaving target mRNA. This study investigated whether DNAzymes targeting Bcl-xL enhanced the effectiveness of radiotherapy and ch...

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Detalles Bibliográficos
Autores principales: Yu, Zhen, Guo, Jun, Meng, Tao, Ge, Lei, Liu, Lin, Wang, Haijiang, Yang, Xinhui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817578/
https://www.ncbi.nlm.nih.gov/pubmed/35123593
http://dx.doi.org/10.1186/s40360-022-00553-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817578/
https://www.ncbi.nlm.nih.gov/pubmed/35123593
http://dx.doi.org/10.1186/s40360-022-00553-x

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