Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice

BACKGROUND: Primaquine (PQ) has been used for the radical cure of relapsing Plasmodium vivax malaria for more than 60 years. PQ is also recommended for prophylaxis and prevention of transmission of Plasmodium falciparum. However, clinical utility of PQ has been limited due to toxicity in individuals...

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Detalles Bibliográficos
Autores principales: Fasinu, Pius S., Chaurasiya, Narayan D., Dhammika Nanayakkara, N. P., Wang, Yan‑Hong, Bandara Herath, H. M. T., Avula, Bharathi, McChesney, James D., Jollow, David, Walker, Larry A., Tekwani, Babu L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817607/
https://www.ncbi.nlm.nih.gov/pubmed/35123453
http://dx.doi.org/10.1186/s12936-022-04054-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817607/
https://www.ncbi.nlm.nih.gov/pubmed/35123453
http://dx.doi.org/10.1186/s12936-022-04054-4

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