Cargando…

Comparative pharmacokinetics and tissue distribution of primaquine enantiomers in mice

BACKGROUND: Primaquine (PQ) has been used for the radical cure of relapsing Plasmodium vivax malaria for more than 60 years. PQ is also recommended for prophylaxis and prevention of transmission of Plasmodium falciparum. However, clinical utility of PQ has been limited due to toxicity in individuals...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fasinu, Pius S., Chaurasiya, Narayan D., Dhammika Nanayakkara, N. P., Wang, Yan‑Hong, Bandara Herath, H. M. T., Avula, Bharathi, McChesney, James D., Jollow, David, Walker, Larry A., Tekwani, Babu L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817607/ https://www.ncbi.nlm.nih.gov/pubmed/35123453 http://dx.doi.org/10.1186/s12936-022-04054-4

Ejemplares similares

Formation primaquine-5,6-orthoquinone, the putative active and toxic metabolite of primaquine via direct oxidation in human erythrocytes
por: Fasinu, Pius S., et al.
Publicado: (2019)

Differential kinetic profiles and metabolism of primaquine enantiomers by human hepatocytes
por: Fasinu, Pius S., et al.
Publicado: (2016)

Comparative single dose pharmacokinetics and metabolism of racemic primaquine and its enantiomers in human volunteers
por: Khan, Washim, et al.
Publicado: (2022)

Pathway-specific inhibition of primaquine metabolism by chloroquine/quinine
por: Fasinu, Pius S., et al.
Publicado: (2016)

Comparative metabolism and tolerability of racemic primaquine and its enantiomers in human volunteers during 7-day administration
por: Khan, Washim, et al.
Publicado: (2023)

Enantioselective metabolism of primaquine by human CYP2D6
por: Fasinu, Pius S, et al.
Publicado: (2014)

Metabolism of primaquine in normal human volunteers: investigation of phase I and phase II metabolites from plasma and urine using ultra-high performance liquid chromatography-quadrupole time-of-flight mass spectrometry
por: Avula, Bharathi, et al.
Publicado: (2018)

Enantioselective Interactions of Anti-Infective 8-Aminoquinoline Therapeutics with Human Monoamine Oxidases A and B †
por: Chaurasiya, Narayan D., et al.
Publicado: (2021)

Monoamine Oxidase Inhibitory Constituents of Propolis: Kinetics and Mechanism of Inhibition of Recombinant Human MAO-A and MAO-B
por: Chaurasiya, Narayan D., et al.
Publicado: (2014)

Hydroxylated Derivatives of NPC1161: Theoretical Insights into Their Potential Toxicity and the Feasibility and Regioselectivity of Their Formation
por: Ding, Yuanqing, et al.
Publicado: (2014)

Natural Products Inhibitors of Monoamine Oxidases—Potential New Drug Leads for Neuroprotection, Neurological Disorders, and Neuroblastoma
por: Chaurasiya, Narayan D., et al.
Publicado: (2022)

Pharmacokinetic Interactions between Primaquine and Chloroquine
por: Pukrittayakamee, Sasithon, et al.
Publicado: (2014)

Pharmacokinetics of chloroquine and primaquine in healthy volunteers
por: Daher, André, et al.
Publicado: (2022)

Population Pharmacokinetics of Primaquine in the Korean Population
por: Lee, Woo-Yul, et al.
Publicado: (2021)

NPC1161B, an 8-Aminoquinoline Analog, Is Metabolized in the Mosquito and Inhibits Plasmodium falciparum Oocyst Maturation
por: Hamerly, Timothy, et al.
Publicado: (2019)

Interactions of Desmethoxyyangonin, a Secondary Metabolite from Renealmia alpinia, with Human Monoamine Oxidase-A and Oxidase-B
por: Chaurasiya, Narayan D., et al.
Publicado: (2017)

Primaquine Pharmacokinetics in Lactating Women and Breastfed Infant Exposures
por: Gilder, Mary Ellen, et al.
Publicado: (2018)

Special Issue: “James D. McChesney, Vision, Passion and Leadership in the Development of Plant-Derived Natural Products”
por: Walker, Larry A., et al.
Publicado: (2021)

Computational Study on the Effect of Exocyclic Substituents on the Ionization Potential of Primaquine: Insights into the Design of Primaquine-Based Antimalarial Drugs with Less Methemoglobin Generation
por: Liu, Haining, et al.
Publicado: (2014)

Selective Inhibition of Human Monoamine Oxidase B by Acacetin 7-Methyl Ether Isolated from Turnera diffusa (Damiana)
por: Chaurasiya, Narayan D., et al.
Publicado: (2019)

Pharmacokinetics of single-dose primaquine in patients with chronic kidney dysfunction
por: Kulkarni, Shaunak P., et al.
Publicado: (2013)

Pharmacokinetics/pharmacodynamics of chloroquine and artemisinin-based combination therapy with primaquine
por: Daher, André, et al.
Publicado: (2019)

Mechanistic Modeling of Primaquine Pharmacokinetics, Gametocytocidal Activity, and Mosquito Infectivity
por: Chotsiri, Palang, et al.
Publicado: (2022)

Studies on Pharmacokinetic Drug Interaction Potential of Vinpocetine
por: Manda, Vamshi K., et al.
Publicado: (2015)

Simplified and Rapid Determination of Primaquine and 5,6-Orthoquinone Primaquine by UHPLC-MS/MS: Its Application to a Pharmacokinetic Study
por: Pookmanee, Waritda, et al.
Publicado: (2021)

Population pharmacokinetics of primaquine and the effect of hepatic and renal dysfunction: An exploratory approach
por: Sridharan, Kannan, et al.
Publicado: (2019)

Enantiomer specific pharmacokinetics of ibuprofen in preterm neonates with patent ductus arteriosus
por: Engbers, Aline G.J., et al.
Publicado: (2020)

Oleanolic acid acrylate elicits antidepressant-like effect mediated by 5-HT(1A) receptor
por: Fajemiroye, James O., et al.
Publicado: (2015)

Selective Interactions of O-Methylated Flavonoid Natural Products with Human Monoamine Oxidase-A and -B
por: Chaurasiya, Narayan D., et al.
Publicado: (2020)

Promising selective MAO-B inhibition by sesamin, a lignan from Zanthoxylum flavum stems
por: Mohamed, Shaymaa M., et al.
Publicado: (2020)

Pharmacokinetic Interactions between Primaquine and Pyronaridine-Artesunate in Healthy Adult Thai Subjects
por: Jittamala, Podjanee, et al.
Publicado: (2014)

Enantiospecific pharmacokinetics and drug–drug interactions of primaquine and blood-stage antimalarial drugs
por: Chairat, Kalayanee, et al.
Publicado: (2018)

Absence of gender influence on the pharmacokinetics of chloroquine combined with primaquine in malaria vivax patients
por: Vieira, Michelle Valeria Dias Ferreira, et al.
Publicado: (2020)

Pharmacokinetics of single low dose primaquine in Ugandan and Congolese children with falciparum malaria
por: Mukaka, Mavuto, et al.
Publicado: (2023)

Pitolisant and Other Histamine-3 Receptor Antagonists—An Update on Therapeutic Potentials and Clinical Prospects
por: Harwell, Victoria, et al.
Publicado: (2020)

In vitro and in vivo anti-malarial activity of tigecycline, a glycylcycline antibiotic, in combination with chloroquine
por: Sahu, Rajnish, et al.
Publicado: (2014)

Screening North American plant extracts in vitro against Trypanosoma brucei for discovery of new antitrypanosomal drug leads
por: Jain, Surendra, et al.
Publicado: (2016)

Antiplasmodial and Cytotoxic Cytochalasins from an Endophytic Fungus, Nemania sp. UM10M, Isolated from a Diseased Torreya taxifolia Leaf
por: Kumarihamy, Mallika, et al.
Publicado: (2019)

Direct-Acting Oral Anticoagulants and Their Reversal Agents—An Update
por: Kustos, Stephanie A., et al.
Publicado: (2019)

Herbal Interaction With Chemotherapeutic Drugs—A Focus on Clinically Significant Findings
por: Fasinu, Pius S., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_mkh5n28n10pekj6u1sf6o7aaei