Eyes on Lipinski's Rule of Five: A New “Rule of Thumb” for Physicochemical Design Space of Ophthalmic Drugs

The study objective was to investigate molecular thermodynamic properties of approved ophthalmic drugs and derive a framework outlining physicochemical design space for product development. Unlike the methodology used to obtain molecular descriptors for assessment of drug-like properties by Lipinski...

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Detalles Bibliográficos
Autores principales: Karami, Thomas K., Hailu, Shumet, Feng, Shaoxin, Graham, Richard, Gukasyan, Hovhannes J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817695/
https://www.ncbi.nlm.nih.gov/pubmed/34905402
http://dx.doi.org/10.1089/jop.2021.0069

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817695/
https://www.ncbi.nlm.nih.gov/pubmed/34905402
http://dx.doi.org/10.1089/jop.2021.0069

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