Quantification of Antisense Oligonucleotides by Splint Ligation and Quantitative Polymerase Chain Reaction

Reliable detection and quantification of antisense oligonucleotides (ASOs) in experimental and clinical specimens are essential to understand the biological function of novel oligonucleotide-based therapeutics. In this study, we describe a method to detect and quantify ASOs in biological samples, wh...

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Detalles Bibliográficos
Autores principales: Shin, Minwook, Meda Krishnamurthy, Pranathi, Devi, Gitali, Watts, Jonathan K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817697/
https://www.ncbi.nlm.nih.gov/pubmed/34928745
http://dx.doi.org/10.1089/nat.2021.0040

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817697/
https://www.ncbi.nlm.nih.gov/pubmed/34928745
http://dx.doi.org/10.1089/nat.2021.0040

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