Antisense Oligonucleotide-Mediated Silencing of Mitochondrial Fusion and Fission Factors Modulates Mitochondrial Dynamics and Rescues Mitochondrial Dysfunction

Mitochondria are highly dynamic organelles that produce ATP and maintain metabolic, catabolic, and redox homeostasis. Mitochondria owe this dynamic nature to their constant fission and fusion—processes that are regulated, in part, by fusion factors (MFN1 and MFN2) and fission factors (DRP1, FIS1, MF...

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Detalles Bibliográficos
Autores principales: Garcia, Daniel A., Powers, Andrew F., Bell, Thomas A., Guo, Shuling, Aghajan, Mariam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Original Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817704/
https://www.ncbi.nlm.nih.gov/pubmed/34698563
http://dx.doi.org/10.1089/nat.2021.0029

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817704/
https://www.ncbi.nlm.nih.gov/pubmed/34698563
http://dx.doi.org/10.1089/nat.2021.0029

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