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Once-Daily Topical Phosphosulindac Is Efficacious in the Treatment of Dry Eye Disease: Studies in Rabbit Models of Its Main Clinical Subtypes

Purpose: Dry eye disease (DED) is classified as aqueous deficient, evaporative, or mixed. We investigated the therapeutic effect of the novel anti-inflammatory drug phosphosulindac (PS) in rabbit models of DED encompassing its pathogenesis, and its transition to chronicity. Methods: We treated three...

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Detalles Bibliográficos
Autores principales: Huang, Wei, Huang, Liqun, Li, Wenyi, Saglam, M. Sait, Tourmouzis, Konstantinos, Goldstein, Sanford M., Master, Adam, Honkanen, Robert, Rigas, Basil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc., publishers 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8817715/
https://www.ncbi.nlm.nih.gov/pubmed/34964663
http://dx.doi.org/10.1089/jop.2021.0050