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A tumor-derived type III collagen-rich ECM niche regulates tumor cell dormancy
Cancer cells disseminate and seed in distant organs, where they can remain dormant for many years before forming clinically detectable metastases. Here we studied how disseminated tumor cells (DTCs) sense and remodel the extracellular matrix (ECM) to sustain dormancy. ECM proteomics revealed that do...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818089/ https://www.ncbi.nlm.nih.gov/pubmed/35121989 http://dx.doi.org/10.1038/s43018-021-00291-9 |