Elucidating tumor-stromal metabolic crosstalk in colorectal cancer through integration of constraint-based models and LC-MS metabolomics

Colorectal cancer (CRC) is a major cause of morbidity and mortality in the United States. Tumor-stromal metabolic crosstalk in the tumor microenvironment promotes CRC development and progression, but exactly how stromal cells, in particular cancer-associated fibroblasts (CAFs), affect the metabolism...

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Detalles Bibliográficos
Autores principales: Wang, Junmin, Delfarah, Alireza, Gelbach, Patrick E., Fong, Emma, Macklin, Paul, Mumenthaler, Shannon M., Graham, Nicholas A., Finley, Stacey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818109/
https://www.ncbi.nlm.nih.gov/pubmed/34838998
http://dx.doi.org/10.1016/j.ymben.2021.11.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818109/
https://www.ncbi.nlm.nih.gov/pubmed/34838998
http://dx.doi.org/10.1016/j.ymben.2021.11.006

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