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Duloxetine in OsteoArthritis (DOA) study: effects of duloxetine on pain and function in end-stage hip and knee OA – a pragmatic enriched randomized controlled trial

BACKGROUND: Some osteoarthritis (OA) patients experience inadequate pain relief from analgesics like acetaminophen and nonsteroidal anti-inflammatory drugs. This could be the result of experienced non-nociceptive centralized pain. Placebo-controlled randomized trials (RCT) have proven the effectiven...

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Detalles Bibliográficos
Autores principales: Blikman, T., Rienstra, W., van Raaij, T. M., ten Hagen, A. J., Dijkstra, B., Zijlstra, W. P., Bulstra, S. K., Stevens, M., van den Akker-Scheek, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818142/
https://www.ncbi.nlm.nih.gov/pubmed/35123461
http://dx.doi.org/10.1186/s12891-022-05034-0