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CENPF/CDK1 signaling pathway enhances the progression of adrenocortical carcinoma by regulating the G2/M-phase cell cycle

BACKGROUND: Adrenocortical carcinoma (ACC) is an aggressive and rare malignant tumor and is prone to local invasion and metastasis. And, overexpressed Centromere Protein F (CENPF) is closely related to the oncogenesis of various neoplasms, including ACC. However, the prognosis and exact biological f...

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Detalles Bibliográficos
Autores principales: Huang, Yu-gang, Li, Dan, Wang, Li, Su, Xiao-min, Tang, Xian-bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818156/
https://www.ncbi.nlm.nih.gov/pubmed/35123514
http://dx.doi.org/10.1186/s12967-022-03277-y