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Macitentan attenuates cardiovascular remodelling in infant rats with chronic lung disease
BACKGROUND: Cardiovascular impairment contributes to increased mortality in preterm infants with chronic lung disease. Macitentan, an endothelin-1 receptor antagonist, has the potential to attenuate pulmonary and cardiovascular remodelling. METHODS: In a prospective randomized placebo-controlled int...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818179/ https://www.ncbi.nlm.nih.gov/pubmed/35123510 http://dx.doi.org/10.1186/s12967-022-03281-2 |