Cargando…
Macitentan attenuates cardiovascular remodelling in infant rats with chronic lung disease
BACKGROUND: Cardiovascular impairment contributes to increased mortality in preterm infants with chronic lung disease. Macitentan, an endothelin-1 receptor antagonist, has the potential to attenuate pulmonary and cardiovascular remodelling. METHODS: In a prospective randomized placebo-controlled int...
Autores principales: | Baumann, Philipp, Greco, Francesco, Wiegert, Susanne, Wellmann, Sven, Pellegrini, Giovanni, Cannizzaro, Vincenzo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818179/ https://www.ncbi.nlm.nih.gov/pubmed/35123510 http://dx.doi.org/10.1186/s12967-022-03281-2 |
Ejemplares similares
-
Hyperoxia-induced lung structure–function relation, vessel rarefaction, and cardiac hypertrophy in an infant rat model
por: Greco, Francesco, et al.
Publicado: (2019) -
Mechanical ventilation strategies alter cardiovascular biomarkers in an infant rat model
por: Baumann, Philipp, et al.
Publicado: (2018) -
Comparison of Macitentan and Bosentan on Right Ventricular Remodeling in a Rat Model of Non-vasoreactive Pulmonary Hypertension
por: Iglarz, Marc, et al.
Publicado: (2015) -
Effects of bergapten on the pharmacokinetics of macitentan in rats both in vitro and in vivo
por: Xu, Jia, et al.
Publicado: (2023) -
Macitentan for the treatment of pulmonary arterial hypertension
por: Kholdani, Cyrus A, et al.
Publicado: (2014)