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Importance of TP53 codon 72 and intron 3 duplication 16 bp polymorphisms and their haplotypes in susceptibility to sarcopenia in Iranian older adults

BACKGROUND: Sarcopenia is described as age-related progressive skeletal muscle failure that results in marked reduction in the patient’s independence and life quality. In this study, we explored the association of TP53 exon 4 Arg72pro (rs1042522) and Intron 3 16-bp Del/Ins (rs17878362) polymorphisms...

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Detalles Bibliográficos
Autores principales: Montazeri-Najafabady, Nima, Dabbaghmanesh, Mohammad Hossein, Nasimi, Nasrin, Sohrabi, Zahra, Estedlal, Alireza, Asmarian, Naeimehossadat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818191/
https://www.ncbi.nlm.nih.gov/pubmed/35123410
http://dx.doi.org/10.1186/s12877-022-02765-6