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Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development

BACKGROUND: Glioblastoma is the most aggressive and common malignant primary brain tumor in adults. Many genetic, epigenetic and genomic mutations have been identified in this tumor, but no driving cause has been identified yet for glioblastoma pathogenesis. Autophagy has proved to be deregulated in...

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Detalles Bibliográficos
Autores principales: Bueno-Martínez, E., Lara-Almunia, M., Rodríguez-Arias, C., Otero-Rodríguez, A., Garfias-Arjona, S., González-Sarmiento, R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818195/
https://www.ncbi.nlm.nih.gov/pubmed/35123435
http://dx.doi.org/10.1186/s12885-022-09214-y