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Polymorphisms in autophagy genes are genetic susceptibility factors in glioblastoma development
BACKGROUND: Glioblastoma is the most aggressive and common malignant primary brain tumor in adults. Many genetic, epigenetic and genomic mutations have been identified in this tumor, but no driving cause has been identified yet for glioblastoma pathogenesis. Autophagy has proved to be deregulated in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818195/ https://www.ncbi.nlm.nih.gov/pubmed/35123435 http://dx.doi.org/10.1186/s12885-022-09214-y |