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Weighted composite time to event endpoints with recurrent events: comparison of three analytical approaches

BACKGROUND: In clinical trials the study interest often lies in the comparison of a treatment to a control regarding a time to event endpoint. A composite endpoint allows to consider several time to event endpoints at once. Usually, only the time to the first occurring event for a patient is thereby...

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Detalles Bibliográficos
Autores principales: Ozga, Ann-Kathrin, Rauch, Geraldine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818231/
https://www.ncbi.nlm.nih.gov/pubmed/35123397
http://dx.doi.org/10.1186/s12874-022-01511-1