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Multimodal approaches for the improvement of the cellular folding of a recombinant iron regulatory protein in E. coli
BACKGROUND: During the recombinant protein expression, most heterologous proteins expressed in E. coli cell factories are generated as insoluble and inactive aggregates, which prohibit E. coli from being employed as an expression host despite its numerous advantages and ease of use. The yeast mitoch...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818239/ https://www.ncbi.nlm.nih.gov/pubmed/35123481 http://dx.doi.org/10.1186/s12934-022-01749-w |