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Design, synthesis, and computational studies of phenylacetamides as antidepressant agents

In the present work, a hit molecule obtained from zinc ‘clean drug-like database’ by systematically performed computational studies was modified chemically to obtain different derivatives (VS1–VS25). Structures of synthesized derivatives were confirmed by IR, (1)H-NMR, (13)C-NMR, (13)C-DEPT, MS, and...

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Detalles Bibliográficos
Autores principales: Suryawanshi, M. R., Kanhed, A. M., Kulkarni, V. M., Bhosale, S. H., Yadav, M. R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818363/
https://www.ncbi.nlm.nih.gov/pubmed/35128584
http://dx.doi.org/10.1007/s11030-021-10374-5