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Design, synthesis, and computational studies of phenylacetamides as antidepressant agents
In the present work, a hit molecule obtained from zinc ‘clean drug-like database’ by systematically performed computational studies was modified chemically to obtain different derivatives (VS1–VS25). Structures of synthesized derivatives were confirmed by IR, (1)H-NMR, (13)C-NMR, (13)C-DEPT, MS, and...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818363/ https://www.ncbi.nlm.nih.gov/pubmed/35128584 http://dx.doi.org/10.1007/s11030-021-10374-5 |