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Distinct roles in phagocytosis of the early and late increases of cell surface calreticulin induced by oxaliplatin

Calreticulin (CRT), a chaperone typically located in the endoplasmic reticulum (ER), is known to translocate to the cell surface in response to anticancer drugs. Cell surface CRT (ecto-CRT) on apoptotic or pre-apoptotic cells serves as an “eat me” signal that can promote phagocytosis. In this study,...

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Detalles Bibliográficos
Autores principales: Matsusaka, Kenju, Azuma, Yutaro, Kaga, Yuki, Uchida, Saeka, Takebayashi, Yuri, Tsuyama, Takashi, Tada, Shusuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818541/
https://www.ncbi.nlm.nih.gov/pubmed/35146135
http://dx.doi.org/10.1016/j.bbrep.2022.101222