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C/EBPβ promotes the expression of atrophy‐inducing factors by tumours and is a central regulator of cancer cachexia

BACKGROUND: CCAAT/enhancer‐binding protein β (C/EBPβ) is a transcription factor whose high expression in human cancers is associated with tumour aggressiveness and poor outcomes. Most advanced cancer patients will develop cachexia, characterized by loss of skeletal muscle mass. In response to secret...

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Detalles Bibliográficos
Autores principales: AlSudais, Hamood, Rajgara, Rashida, Saleh, Aisha, Wiper‐Bergeron, Nadine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818591/
https://www.ncbi.nlm.nih.gov/pubmed/35014202
http://dx.doi.org/10.1002/jcsm.12909