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Chronic aryl hydrocarbon receptor activity phenocopies smoking‐induced skeletal muscle impairment

BACKGROUND: Chronic obstructive pulmonary disease (COPD) patients exhibit skeletal muscle atrophy, denervation, and reduced mitochondrial oxidative capacity. Whilst chronic tobacco smoke exposure is implicated in COPD muscle impairment, the mechanisms involved are ambiguous. The aryl hydrocarbon rec...

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Detalles Bibliográficos
Autores principales: Thome, Trace, Miguez, Kayla, Willms, Alexander J., Burke, Sarah K., Chandran, Vijayendran, de Souza, Angela R., Fitzgerald, Liam F., Baglole, Carolyn, Anagnostou, Maria‐Eleni, Bourbeau, Jean, Jagoe, R. Thomas, Morais, Jose A., Goddard, Yana, Taivassalo, Tanja, Ryan, Terence E., Hepple, Russell T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818603/
https://www.ncbi.nlm.nih.gov/pubmed/34725955
http://dx.doi.org/10.1002/jcsm.12826