Ameliorating cancer cachexia by inhibiting cancer cell release of Hsp70 and Hsp90 with omeprazole

BACKGROUND: Cancer cachexia, characterized by muscle and fat tissue wasting, is a major determinant of cancer‐related mortality without established treatment. Recent animal data revealed that cancer cells induce muscle wasting by releasing Hsp70 and Hsp90 as surface proteins on extracellular vesicle...

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Detalles Bibliográficos
Autores principales: Liu, Zhelong, Xiong, Jian, Gao, Song, Zhu, Michael X., Sun, Kai, Li, Min, Zhang, Guohua, Li, Yi‐Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles: Basic Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818607/
https://www.ncbi.nlm.nih.gov/pubmed/34729960
http://dx.doi.org/10.1002/jcsm.12851

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818607/
https://www.ncbi.nlm.nih.gov/pubmed/34729960
http://dx.doi.org/10.1002/jcsm.12851

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