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Syndecan-4 affects myogenesis via Rac1-mediated actin remodeling and exhibits copy-number amplification and increased expression in human rhabdomyosarcoma tumors

Skeletal muscle demonstrates a high degree of regenerative capacity repeating the embryonic myogenic program under strict control. Rhabdomyosarcoma is the most common sarcoma in childhood and is characterized by impaired muscle differentiation. In this study, we observed that silencing the expressio...

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Detalles Bibliográficos
Autores principales: Szabo, Kitti, Varga, Daniel, Vegh, Attila Gergely, Liu, Ning, Xiao, Xue, Xu, Lin, Dux, Laszlo, Erdelyi, Miklos, Rovo, Laszlo, Keller-Pinter, Aniko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818642/
https://www.ncbi.nlm.nih.gov/pubmed/35128576
http://dx.doi.org/10.1007/s00018-021-04121-0