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Renal failure suppresses muscle irisin expression, and irisin blunts cortical bone loss in mice

BACKGROUND: Chronic renal failure induces bone mineral disorders and sarcopenia. Skeletal muscle affects other tissues, including bone, by releasing myokines. However, the effects of chronic renal failure on the interactions between muscle and bone remain unclear. METHODS: We investigated the effect...

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Detalles Bibliográficos
Autores principales: Kawao, Naoyuki, Kawaguchi, Miku, Ohira, Takashi, Ehara, Hiroki, Mizukami, Yuya, Takafuji, Yoshimasa, Kaji, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818650/
https://www.ncbi.nlm.nih.gov/pubmed/34997830
http://dx.doi.org/10.1002/jcsm.12892