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Ovarian cancer ascites induces skeletal muscle wasting in vitro and reflects sarcopenia in patients

BACKGROUND: Cachexia‐associated skeletal muscle wasting or ‘sarcopenia’ is highly prevalent in ovarian cancer and contributes to poor outcome. Drivers of cachexia‐associated sarcopenia in ovarian cancer remain elusive, underscoring the need for novel and better models to identify tumour factors indu...

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Detalles Bibliográficos
Autores principales: Ubachs, Jorne, van de Worp, Wouter R.P.H., Vaes, Rianne D.W., Pasmans, Kenneth, Langen, Ramon C., Meex, Ruth C.R., van Bijnen, Annemarie A.J.H.M., Lambrechts, Sandrina, Van Gorp, Toon, Kruitwagen, Roy F.P.M., Olde Damink, Steven W.M., Rensen, Sander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8818657/
https://www.ncbi.nlm.nih.gov/pubmed/34951138
http://dx.doi.org/10.1002/jcsm.12885